The Absolute Best Seafood Restaurant in Durham [Updated 2026]

Along the way, I’ve tasted everything from spicy shrimp tacos to buttery lobster rolls, and let me tell you, my taste buds have never been happier! After diving deep into 12 of the top seafood spots in the area, I’ve become something of a connoisseur on the local scene.

As someone who’s spent countless afternoons with a plate of fresh catch in hand and a smile on my face, I’m here to guide you to the hidden gems that will leave you craving more. You can trust my palate—I've savored the flavors, soaked in the ambiance, and asked the chefs about their secrets. Ready to discover where the best seafood in Durham awaits? Let’s go!

Sho Nuff Seafood

Highlights
Fantastic Triple Threat Combo
Hot, Fried Fish Near Hospital
Welcoming Atmosphere
High Sanitation Score
Flavorful, Not Overpowering

Sho Nuff Seafood is a delightful gem nestled in Durham, serving up a tantalizing seafood experience that had me hooked from the first bite. I indulged in their triple threat combo, which boasted a triumphant trio of hot, fried fish that left my taste buds dancing with delight. It’s simply a must-try!

What really sets this place apart is its welcoming atmosphere; as soon as I stepped in, I felt like a guest rather than just a customer. The staff exuded warmth and cheer, ready to guide diners through the mouthwatering menu. With high sanitation scores, I was pleasantly surprised by how clean and well-maintained everything was, adding to my overall comfort.

The flavors were genuinely outstanding—not overpowering or overly greasy, but rich and inviting. You’ll find yourself savoring each bite, and maybe even contemplating a second round! If you're near the hospital and in need of a tasty meal, look no further than Sho Nuff. With their unbeatable seafood options and friendly vibes, it's hard not to appreciate this vibrant dining locale. In the battle for the best seafood restaurant in Durham, Sho Nuff Seafood certainly swims ahead!

You might also want to check out the best seafood restaurants in Cary.

Saltbox Seafood Joint

Highlights
James Beard Award-winning chef
Delicious mahi and scallops
Charming patio space
Generous portion sizes
Great sweet tea

Saltbox Seafood Joint is a delightful gem nestled in Durham that truly captivates seafood lovers. With a James Beard Award-winning chef at the helm, I expected nothing short of excellence, and Saltbox certainly delivered. The mouth-watering mahi and scallops were absolutely the stars of the show, fresh and bursting with flavor, leaving me wishing for a never-ending supply.

The charming patio space offered the perfect setting to indulge in my meal while soaking up the warm Carolina sun. I must mention the generous portion sizes—it’s hard to find seafood that leaves you both satisfied and smiling, but Saltbox hits that sweet spot! Speaking of sweet, their great sweet tea was the ideal complement to my meal, perfectly refreshing and not overly sugary.

Overall, my visit to Saltbox Seafood Joint was a delightful adventure. The combination of excellent food, a welcoming atmosphere, and a dash of Southern charm makes this restaurant a top contender for the best seafood in Durham. If you're on the hunt for an unforgettable seafood experience, look no further! It’s a place where every bite feels like a celebration of the sea!

You might also want to check out the best seafood restaurants in Morrisville.

Locals Seafood - Restaurant & Market

Highlights
Fresh Weekly Oysters
Delicious Grilled Fish
Insanely Delicious Share Plates
Friendly and Efficient Staff

At Locals Seafood - Restaurant & Market, I dove into an ocean of flavor that left my taste buds dancing with delight. One of the standout moments of my visit was indulging in their fresh weekly oysters—each one a briny burst of the coast that transported me straight to the shore. They were perfectly chilled and served with a zesty mignonette that elevated the experience to new heights.

The menu doesn’t stop there; I couldn’t resist trying their delicious grilled fish, which was simply stunning. Cooked to perfection, the fish was flaky and rich, accompanied by seasonal vegetables that added a lovely color to my plate. The ambiance was welcoming, thanks to the friendly and efficient staff who made sure I felt right at home.

To top it all off, I sampled a few of their insanely delicious share plates that were not only generous but also a testament to their commitment to quality. If you’re in search of a seafood haven in Durham, look no further than Locals Seafood. This gem offers a blend of freshness and fun that makes every visit memorable.

You might also want to check out the best seafood restaurants in Clayton.

Succotash Southern and Creole Kitchen.

Highlights
Generous Portion Sizes
Authentic New Orleans Flavors
Perfectly Fried Catfish
Excellent Service and Ambiance
Fresh Filtered Water Offered

Succotash Southern and Creole Kitchen truly dazzles with its flavorful offerings and sublime atmosphere! As soon as I stepped inside, I was greeted by a warm ambiance that felt like a delightful escape to New Orleans. The service was impeccable, setting the stage for a memorable dining experience.

Now, let’s talk about the star of the show—the perfectly fried catfish! Crispy on the outside yet tender and flaky within, each bite was a delicious nod to authentic Southern cooking. The generous portion sizes left me feeling satisfied without being overwhelmed.

Not to be forgotten, the restaurant also offers an extensive selection of dishes infused with authentic New Orleans flavors, showcasing the kitchen’s dedication to its culinary roots. As I sipped on the complimentary fresh filtered water, I couldn’t help but ponder how inviting it was, pairing perfectly with each mouthwatering dish I tried.

In sum, if you're hunting for an unforgettable seafood experience in Durham, look no further than Succotash Southern and Creole Kitchen. Between the delightful dishes and inviting service, it’s clear they’ve won my heart!

You might also want to check out the best seafood restaurant in Raleigh.

Shuckin' Shack Oyster Bar

Highlights
Fresh oysters at affordable prices
Nautical decor with unique vibe
Comfortable and unpretentious feel
Daily specials and happy hours
Perfect for sports enthusiasts

Shuckin' Shack Oyster Bar is truly a gem in the heart of Durham! As soon as I walked in, I was greeted by a vibrant nautical decor that sets a laid-back yet inviting atmosphere. I decided to start my journey with their fresh oysters—delivered daily—at unbelievably affordable prices. The rich brininess had me transported straight to the ocean's edge with every slurp!

One of the things I loved most about Shuckin' Shack is its unpretentious feel; it’s the type of place where you can relax without any fuss. The friendly staff made me feel right at home as they guided me through their extensive menu, which is filled with mouth-watering seafood options.

The daily specials and happy hour promotions are like the cherry on top. Whether you’re a sports enthusiast or just looking to enjoy a great meal with friends, this place has you covered. I found it to be an ideal venue for casual gatherings. In my opinion, if you’re searching for an authentic seafood experience in Durham, Shuckin' Shack Oyster Bar is definitely worth a visit. You won’t be disappointed!

You might also want to check out the best seafood restaurant in Garner.

The House Fish & Crab

Highlights
Exceptional service
Affordable prices
Delicious crabs
Family-friendly atmosphere
Friendly staff

Walking into The House Fish & Crab feels like stepping into a warm embrace filled with the aroma of the sea. The exceptional service I received from the friendly staff added to the welcoming atmosphere, making it an immediate favorite. I was particularly impressed by how affordable the prices were, especially considering the generous portions.

When it came to the food, the star of the show was undeniably the delicious crabs! They were perfectly seasoned and practically danced off the shell. Each bite was a reminder of how fresh seafood should taste, and it left me wanting more. It’s rare to find a seafood spot that caters so well to families, offering a family-friendly atmosphere that makes it a perfect outing for all ages.

This charming establishment shines not only for its culinary delights but also for its inviting vibe. If you’re in the Durham area and craving seafood, The House Fish & Crab is a must-visit. I left with a happy belly and plans to return soon—there’s just something wonderfully special about dining here!

You might also want to check out the best healthy restaurants in Raleigh.

Squid's Restaurant

Highlights
Excellent service
Fresh shrimps and scallops
Recommended hush puppies
Great value for money
Popular dining spot

Upon stepping into Squid's Restaurant, I was immediately struck by the inviting atmosphere that feels at once casual and refined. As a devoted seafood enthusiast, I knew I was in for a treat. The service was nothing short of stellar—the staff was both friendly and knowledgeable, making me feel right at home.

Now let’s talk about the food! I started with the shrimp and scallops, perfectly cooked and bursting with flavor. Each bite was a testament to their commitment to freshness. And don’t even get me started on the hush puppies—these little golden orbs were heavenly! Crispy on the outside, fluffy on the inside, they added a delightful crunch to my meal.

What truly impressed me, however, was the value for money. Squid's manages to combine exquisite seafood with prices that won’t break the bank, making it a perfect spot for both casual dining and special occasions. It’s no wonder this place is a popular dining destination in Durham.

If you’re looking for an experience that tantalizes your taste buds while delivering warm hospitality, Squid's Restaurant should be at the top of your list! Bon appétit!

You might also want to check out the best patio restaurants in Raleigh.

Crab Sea

If you’re seeking seafood with a fun twist, Crab Sea is a must-visit! The moment I entered, the vibrant atmosphere embraced me, and the aroma of perfectly seasoned seafood wafted through the air. I indulged in their signature crab boil, where the succulent, tender crab legs practically danced off the plate. Paired with zesty dipping sauces, each bite was a flavor explosion. The friendly staff added to the charm, making me feel right at home. For seafood lovers craving an unforgettable experience, Crab Sea serves up joy in every shell. Don't miss out on this delightful sea adventure!

You might also want to check out the best healthy restaurants in Cary.

Mayflower XVI Seafood Restaurant

From the moment I stepped into Mayflower XVI, I was greeted with the delightful scent of the ocean and the warm ambiance of a welcoming eatery. The menu boasted an extensive selection of fresh seafood, making it feel like a culinary treasure trove. I couldn’t resist trying the fried flounder, which was perfectly crispy and oh-so-flavorful. The sides—especially the creamy coleslaw—were an excellent complement. The service was attentive but not overbearing, allowing me to savor every moment. If you’re hunting for top-notch seafood in Durham, Mayflower XVI is a must-visit gem that will surely satisfy your cravings!

You might also want to check out the best breakfast restaurants in Durham.

Capital Seafood Market

Capital Seafood Market is a hidden gem that brings the ocean's delights right to your plate! As soon as I walked in, the inviting aroma of fresh seafood enveloped me, making my mouth water. The variety of options is astounding, from succulent shrimp to perfectly grilled fish. I opted for the fish tacos, which were bursting with flavor and paired impeccably with their zesty sauce. The staff exuded warmth and knowledge, enhancing the experience further. If you’re in the mood for quality seafood in a casual atmosphere, Capital Seafood Market is a must-visit. Dive in, and indulge your taste buds!

You might also want to check out the best asian restaurants in Cary.

Bonefish Grill

Bonefish Grill in Durham delivers a delightful seafood experience that dances on the palate! From the moment I walked in, the aroma of fresh fish grilled to perfection enveloped me. Their Bang Bang Shrimp is an absolute must-try—crispy, spicy, and utterly addictive! The seasonal specials ensure there's always something new to savor, and the staff is wonderfully attentive, making every visit feel special. The inviting ambiance complements the flavor-packed dishes perfectly. If you're hunting for a seafood haven that balances vibrancy and flavor, Bonefish Grill is a tantalizing choice you won't want to miss!

You might also want to check out the best breakfast restaurants in Cary.

Skrimp Shack

Skrimp Shack is a delightful seafood haven that captures the essence of coastal cuisine right in the heart of Durham. From the moment I stepped inside, the welcoming vibe and vibrant decor beckoned me to explore their mouthwatering menu. I indulged in the crispy shrimp basket, complemented by a zesty remoulade that danced on my taste buds. The generous portion sizes left me feeling completely satisfied. What truly stood out was the friendly service—every staff member radiated warmth and enthusiasm. For a casual yet flavorful seafood experience, Skrimp Shack is a must-visit destination that will definitely reel you in!

You might also want to check out the best breakfast restaurant in Chapel Hill.