The Absolute Best Mexican Restaurant in Clayton [Updated 2025]

The Absolute Best Mexican Restaurant in Clayton  [Updated 2025]
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After diving into the vibrant culinary scene of this charming town, I took it upon myself to explore and review twelve top-notch Mexican restaurants. Each spot had its own unique flair and flavor, but only one truly stood out among the rest. As someone who's savored countless tacos, enchiladas, and margaritas over the years, I’ve developed a discerning palate and a deep appreciation for authentic Mexican cuisine.

You can trust my insights because I’ve not only tasted the dishes but also immersed myself in the atmosphere and service that makes a dining experience unforgettable. So, get ready to join me on this delicious journey as I unveil the hidden gem that will satisfy all your cravings!


El Patron 323 Clayton

El Patron 323 Clayton
🗺️ 905 E Main St, Clayton, NC 27520
☎️ 919-585-2206
🌐 Website
Sunday: 11 AM–9 PM
Monday: 11 AM–9 PM
Tuesday: 11 AM–9 PM
Wednesday: 11 AM–9 PM
Thursday: 11 AM–9 PM
Friday: 11 AM–10 PM
Saturday: 11 AM–10 PM
Highlights
Fresh and delicious entrees
Excellent attention
Inviting decoration
Family-friendly atmosphere
Repeat visits encouraged

Nestled in the heart of Clayton, El Patron 323 is a delightful gem that has captured my taste buds like no other. From the moment I walked in, I was greeted by inviting decorations that set the stage for an authentic culinary adventure. The ambiance is perfect for families and friends alike, making it a great spot for an evening out.

The fresh and delicious entrees here are a testament to the restaurant’s commitment to quality. I savored their signature enchiladas, which were bursting with flavor and smothered in a zesty sauce that left me craving more. Each dish is crafted with care, paying homage to traditional Mexican cuisine while adding a unique twist.

Not only was the food outstanding, but the excellent attention from the staff made my visit feel special. They were genuinely friendly and eager to recommend their favorite dishes, which made the experience even more enjoyable.

After that fantastic meal, I can confidently say that El Patron 323 Clayton is not just another Mexican restaurant; it’s a place where repeat visits are not just encouraged—they're inevitable! If you're looking for your next favorite taco spot, look no further!

You might also want to check out the best mexican restaurants in Chapel Hill.

Taquiza La Guadalupana

Taquiza La Guadalupana
🗺️ 10581 BUS US-70 E, Clayton, NC 27520
☎️ 919-710-5840
🌐 Website
Sunday: Closed
Monday: 3:30–11:30 PM
Tuesday: 3:30–11:30 PM
Wednesday: 3:30–11:30 PM
Thursday: 3:30–11:30 PM
Friday: 3:30–11:30 PM
Saturday: Closed
Highlights
Professional event catering
Amazing homemade tortillas
Pleasing customer service
Generous portions
Convenient to-go containers

Taquiza La Guadalupana has quickly become a standout in my culinary adventures around Clayton. From the moment I stepped in, the inviting aroma of fresh tortillas tantalized my senses. Their homemade tortillas are nothing short of heaven—warm, soft, and bursting with flavor, they elevate every dish.

One of the highlights of my visit was their absolutely generous portions. I couldn’t help but smile as I dug into my plate, proving that this spot not only delights with taste but also fills you up! The customer service was top-notch; staff members were friendly and attentive, making sure I had everything I needed to enjoy my meal.

What truly impressed me was the availability of to-go containers for those in a hurry. You can grab your favorites and still enjoy them later—perfect for busy schedules or impromptu picnics!

With a commitment to professional event catering as well, Taquiza La Guadalupana has earned its reputation as a local gem. Whether you’re dining in or taking out, this restaurant serves up a joyous and authentic Mexican experience that keeps you coming back for more. Highly recommended!

You might also want to check out the best mexican restaurant in Apex.

Mezcalito Clayton

Mezcalito Clayton
🗺️ 229 Briarcliff Dr A, Clayton, NC 27527
☎️ 919-243-0653
🌐 Website
Sunday: 11 AM–9 PM
Monday: 11 AM–9:30 PM
Tuesday: 11 AM–9:30 PM
Wednesday: 11 AM–9:30 PM
Thursday: 11 AM–9:30 PM
Friday: 11 AM–11 PM
Saturday: 11 AM–11 PM

My visit to Mezcalito Clayton was an unforgettable journey through the vibrant flavors of Mexico! The moment I stepped inside, I was greeted by a warm ambiance, filled with the enticing aroma of authentic dishes. I indulged in their signature mole sauce, a rich blend that danced on my palate, and paired it with freshly made tortillas that were just heavenly. The staff’s friendliness was as refreshing as the agave cocktails I sipped. If you're craving an explosion of flavors and a cozy atmosphere, Mezcalito Clayton is a must-visit destination for any taco enthusiast!

You might also want to check out the best vegan restaurants in Raleigh.

La Cocina Clayton

La Cocina Clayton
🗺️ 764 Shotwell Rd, Clayton, NC 27520
☎️ 919-550-7323
🌐 Website
Sunday: 11 AM–9 PM
Monday: 11 AM–10 PM
Tuesday: 11 AM–10 PM
Wednesday: 11 AM–10 PM
Thursday: 11 AM–10 PM
Friday: 11 AM–11 PM
Saturday: 11 AM–11 PM

I recently dined at La Cocina Clayton, and let me tell you, it’s a fiesta for the senses! The vibrant decor sets the stage for a delightful culinary journey. I was mesmerized by their authentic tacos al pastor, bursting with flavor and served with a side of fresh salsa that could make anyone dance. The staff is as warm as the homemade tortillas they serve, making the experience feel like a visit to a friend’s home. If you're looking for a spot that serves up both delicious food and great vibes, La Cocina is a must-try in Clayton!

You might also want to check out the best indian restaurants in Morrisville.

Q’ Chingon Mexican Restobar

Q’ Chingon Mexican Restobar
🗺️ 11617 Clayton Blvd, Clayton, NC 27520
☎️ 919-585-2091
🌐 Website
Sunday: 11 AM–9 PM
Monday: 11 AM–9 PM
Tuesday: 11 AM–9:30 PM
Wednesday: 11 AM–9:30 PM
Thursday: 11 AM–10 PM
Friday: 11 AM–12 AM
Saturday: 12 AM–11 PM

My visit to Q’ Chingon Mexican Restobar was nothing short of delightful! From the moment I stepped in, the vibrant decor and lively atmosphere enveloped me. I savored their mole enchiladas, a beautiful blend of rich flavors that whisked me away to Mexico itself. The salsa verde? A standout, with just the right kick to elevate any dish. The staff exuded warmth and hospitality, making me feel like part of their family. If you're seeking an authentic Mexican culinary adventure, Q’ Chingon is a must-visit—where every bite is a fiesta on your plate!

You might also want to check out the best indian restaurant in Cary.

Fiesta Mexicana Clayton

Fiesta Mexicana Clayton
🗺️ 957 Town Centre Blvd, Clayton, NC 27520
☎️ 919-550-8888
🌐 Website
Sunday: 11 AM–9:30 PM
Monday: 11 AM–10 PM
Tuesday: 11 AM–10 PM
Wednesday: 11 AM–10 PM
Thursday: 11 AM–10 PM
Friday: 11 AM–10:30 PM
Saturday: 11 AM–10:30 PM

Fiesta Mexicana Clayton is a delightful gem that captures the essence of Mexican culture with every bite! The moment I stepped in, the vibrant decor and warm ambiance wrapped around me like a cozy blanket. I indulged in their authentic tacos al pastor, bursting with flavor and generously topped with fresh cilantro and onions. The homemade salsa added just the right kick! Service was friendly and attentive, making me feel right at home. If you’re seeking a true fiesta in flavors and atmosphere, Fiesta Mexicana is a must-visit for anyone craving a taste of Mexico in Clayton. 🍽️🌮

You might also want to check out the best asian restaurants in Cary.

Lil Hombre Smoked Taco Joint

Lil Hombre Smoked Taco Joint
🗺️ 401 E Second St Ste. 113, Clayton, NC 27520
Sunday: 11 AM–11 PM
Monday: 11 AM–11 PM
Tuesday: 11 AM–11 PM
Wednesday: 11 AM–11 PM
Thursday: 11 AM–11 PM
Friday: 11 AM–1 AM
Saturday: 11 AM–1 AM

At Lil Hombre Smoked Taco Joint, every bite is an adventure! The smoky flavors infuse their tacos with an irresistible twist, making even the classic options feel fresh and exciting. I highly recommend trying the brisket taco—it’s a melt-in-your-mouth experience that dances with spices. The vibrant atmosphere and friendly staff make you feel right at home, inviting you to savor every moment. Don’t skip the house-made salsas; they pack a delightful punch! If you’re craving a taco experience like no other, this joint should definitely be at the top of your list! Unforgettable dining awaits here!

You might also want to check out the best indian restaurant in Raleigh.

Guajillo's Mexican Grill

Guajillo's Mexican Grill
🗺️ 8948 Cleveland Rd #102, Clayton, NC 27520
☎️ 919-209-9939
🌐 Website
Sunday: 11 AM–9 PM
Monday: 11 AM–2 PM
Monday: 4–9 PM
Tuesday: 11 AM–2 PM
Tuesday: 4–9 PM
Wednesday: 11 AM–2 PM
Wednesday: 4–9 PM
Thursday: 11 AM–2 PM
Thursday: 4–9 PM
Friday: 11 AM–10 PM
Saturday: 11 AM–10 PM

Guajillo's Mexican Grill is a vibrant gem in Clayton that dances on your taste buds! From the moment I stepped inside, the lively decor and warm aroma of spices wrapped around me like a cozy blanket. I indulged in their authentic carne asada tacos, bursting with flavor and served with the perfect pico de gallo. The service was friendly and attentive, making me feel right at home. Don't skip their house-made guacamole—it’s simply divine! If you're seeking a delightful culinary escape, Guajillo's is where you'll find Mexican cuisine done just right. A must-try for anyone craving a festive feast!

You might also want to check out the best indian restaurant in Chapel Hill.

Green Banana Restaurante Hondureño

Green Banana Restaurante Hondureño
🗺️ 11471 US-70 BUS, Clayton, NC 27520
☎️ 919-243-1649
🌐 Website
Sunday: Closed
Monday: 9 AM–9 PM
Tuesday: 9 AM–9 PM
Wednesday: 9 AM–9 PM
Thursday: 9 AM–9 PM
Friday: 9 AM–10:30 PM
Saturday: 9 AM–10:30 PM

Visiting Green Banana Restaurante Hondureño in Clayton is like taking a culinary trip south of the border! The vibrant atmosphere and colorful décor instantly set the tone. I was pleasantly surprised by their savory tacos bursting with flavor and crafted from fresh ingredients. The secret sauce paired with their crispy plantains was a delightful twist I didn’t expect. The friendly staff made me feel right at home, and the margaritas? Simply unforgettable! While not exclusively a Mexican eatery, the fusion of flavors makes it a worthy contender in Clayton's food scene. A must-try for anyone craving unique Latin flavors!

You might also want to check out the best asian restaurants in Chapel Hill.

Tacos Y Burritos California

Tacos Y Burritos California
🗺️ 11538 US-70 BUS, Clayton, NC 27520
☎️ 919-585-2736
🌐 Website
Sunday: 9 AM–9 PM
Monday: 9 AM–9 PM
Tuesday: 9 AM–9 PM
Wednesday: 9 AM–9 PM
Thursday: 9 AM–9 PM
Friday: 9 AM–9 PM
Saturday: 9 AM–9 PM

Tacos Y Burritos California is a hidden gem in Clayton that had my taste buds dancing! The tacos are a flavorful explosion, with perfectly seasoned meats and a generous sprinkle of fresh toppings that elevate each bite. Their burritos? Simply legendary—stuffed to the brim with delectable fillings and wrapped in a warm, soft tortilla. The vibrant salsa bar adds an extra zing, allowing for personalized flavor adventures. The ambiance is cozy and inviting, making it a perfect spot for casual dining. If you’re craving authentic Mexican fare, this place is a must-visit! Your taste buds will thank you.

You might also want to check out the best italian restaurants in Wake Forest.

Fiesta Mexicana Garner

Fiesta Mexicana Garner
🗺️ 5131 NC-42 #270, Garner, NC 27529
☎️ 919-772-5498
🌐 Website
Sunday: 11 AM–10 PM
Monday: 11 AM–10 PM
Tuesday: 11 AM–10 PM
Wednesday: 11 AM–10 PM
Thursday: 11 AM–10 PM
Friday: 11 AM–11 PM
Saturday: 11 AM–11 PM

Fiesta Mexicana Garner is an absolute delight! The moment you step inside, the vibrant decor and friendly atmosphere engulf you. I dove into their authentic street tacos, bursting with flavor and topped with fresh cilantro and onions—pure bliss! The house-made guacamole was the perfect accompaniment, creamy with just the right kick. Don't skip the margaritas; they’re a refreshing escape. The staff treated us like family, making our experience even more enjoyable. If you're hunting for a culinary fiesta in Clayton, look no further than Fiesta Mexicana. This gem truly elevates the mexican dining scene!

You might also want to check out the best italian restaurants in Chapel Hill.

Taqueria Mi Palmar

Taqueria Mi Palmar
🗺️ 9182 Cleveland Rd, Clayton, NC 27520
☎️ 984-833-9852
Sunday: Closed
Monday: 11 AM–8 PM
Tuesday: 11 AM–8 PM
Wednesday: 11 AM–8 PM
Thursday: 11 AM–5 PM
Friday: 11 AM–8 PM
Saturday: Closed

Taqueria Mi Palmar is a vibrant slice of Mexico tucked in Clayton. From the moment I stepped in, the aroma of fresh ingredients dancing in the air promised a delightful meal. I tried their tacos al pastor, and each bite was a fiesta in my mouth — the marinated pork was succulent, paired perfectly with a tangy pineapple salsa. The atmosphere was buzzing yet welcoming, making it perfect for both solo diners and groups. Don't skip their house-made salsas; they add an extra kick that elevates the entire experience. If you’re craving authentic flavors, this spot deserves a top place on your list!

You might also want to check out the best italian restaurants in Morrisville.

Landon StroudL
WRITTEN BY

Landon Stroud

Landon Stroud is a passionate writer and local enthusiast dedicated to exploring the vibrant culture and hidden gems of Raleigh, North Carolina. With a knack for storytelling, he captures the essence of the city's neighborhoods, food scene, and community events, inviting readers to discover what makes Raleigh unique.

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Food tour map
The Local's Blackbook 📓

The 48-Hour Insider Itinerary to Raleigh

Join our The Raleigh Report newsletter and get our 48-hour insider itinerary to the top hidden spots in Raleigh.

  • Custom 3-stop crawl with QR codes for easy navigation
  • 5 photo-worthy hidden gems (Instagram gold)
  • Insider timing tips: when to go to skip crowds
  • Top spots in your inbox every week
Landon Stroud
Raleigh Black Book
The Local's Blackbook 📓

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Join our The Raleigh Report newsletter and get our 48-hour insider itinerary to the top hidden spots in Raleigh.